Abstract
Metastasis from various neoplasms to the spleen is very rare and most of the cases are found at autopsy. We report a patient presenting with uterine cervical cancer with splenic metastases. A 49-year-old woman presenting with genital bleeding was referred to our hospital and diagnosed with stage IIB cervical cancer. She underwent concomitant chemoradiotherapy (CCRT) consisting of 50 Gy whole pelvis irradiation, high-dose-rate intracavitary brachytherapy 24 Gy/4 fractions and six weeks of paclitaxel and carboplatin administration. Ten months after the initial therapy, CT revealed recurrence at spleen. Although she received 5 courses of nedaplatin, enlargement of the tumor was noticed. She underwent a splenectomy and the result of histology was compatible with metastasis of cervical cancer.
Highlights
Improvement of chemotherapy, irradiation, and surgical treatment has resulted in better control of disease and longer survival of cancer patients and has led to high incidences of distant metastases
Metastasis from cervical cancer to the spleen is very rare and most of the cases are found at autopsy
Carlson et al reported in their review that overall incidence of distant metastasis of 2200 cases of squamous cell carcinoma of the cervix cancer was 15.3% [1]
Summary
Improvement of chemotherapy, irradiation, and surgical treatment has resulted in better control of disease and longer survival of cancer patients and has led to high incidences of distant metastases. Metastasis from cervical cancer to the spleen is very rare and most of the cases are found at autopsy. We report a case of cervical cancer metastasizing to the spleen
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
