Abstract
Abstract A simple chemical test previously described for the determination of total protein and -globulin was applied to the analysis of spinal fluid specimens (CSF) from non-neurologic and a variety of neurologic disorders. On the basis of the chemical findings, the pathologic specimens analyzed were divided into three groups: (a) nonneurologic and some neurologic conditions with a normal CSF total protein and -globulin concentration; (b) demyelinating disorders with a normal total protein and elevated b.gamma;-globulin concentration; and (c) degenerative and infectious with an elevated total protein and -globulin. A good correlation between chemical findings and clinical observation was obtained.
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