Abstract
In November, 1988, 41 of 107 SPF pigs showed pyrexia, anorexia and respiratory signs on an SPF farm which started breeding of SPF pigs 3 months before the occurrence. Ten of the pigs died one to three days after the onset of clinical diseese. At autopsy, a large quantity of yellowish cloudy fluid containing fibrinous exudate was found in the abdominal, thoracic and pericardial cavities. Histopathologically, purulent meningitis, purulent fibrinous polyserositis (pleuritis, pericarditis and peritonitis) and purulent arthritis were observed. Haemophilus parasuis was isolated from some organs, cavity fluid and synovial fluid in five of 11 pigs examined. The isolates were identified as serotype 5 by the gel diffusion method and as PAGE type II by SDS-polyacrylamide gel electrophoresis. These results indicate that the present outbreak was of Glasser's disease. The results of serological examination suggest that the organism may have invaded the SPF farm, and cold stress may have led to a serious enzootic outbreak of the disease with a high morbidity.
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