Spectrum of Non-neoplastic Skin Lesions: A Histopathological Study based on Punch Biopsy (A Study of 200 Cases)

Abstract

Introduction: Accurate diagnosis of skin is of utmost importance for management of different skindisorders presenting with the similar clinical signs and symptoms. Therefore to confirm the diagnosis andstart treatment biopsy becomes inevitable and for obtaining diagnostic full-thickness skin specimens Punchbiopsy is the primary method.Aims & Objective: The present study was to analyse the incidence and age & sex distribution of dermatologicaldisorders presenting to B.J. Medical College, Civil Hospital Ahmedabad (tertiary care centre), Gujarat andaccess their histopathological profileMaterials & Methods: This was a retrospective study carried out at the department of Pathology B.J.Medical College & Civil Hospital, Ahmedabad for a period of 1 year (1st January 2018 to 31st December2018). With necessary clinical details obtained in a proforma, punch biopsy specimen is sent to thehistopathology section for final diagnosis. Formalin fixed, paraffin embedded sections were prepared &slides were routinely stained with H & E and special stains applied wherever necessary. Data obtained wastabulated and analysed.Results: Total 232 cases were analysed. 21-30 years age group constituted 22% of the total cases. Male/Female ratio is 61/39. Hypopigmented patch/plaque was the most common clinical lesion (27%). Hansen’sdisease was the most common histopathological diagnosis reported (30%) followed by vesiculobullouslesions (12%).Conclusion: Punch biopsy is a very simple outdoor procedure and very useful for skin lesions. Hansen’sdisease is still most common skin disease for which biopsy is done followed by vesiculobullous lesion.Tattoo induced granuloma is also a common lesion along with lichenoid lesion.