Spectrophotometric determination of sodium-copper chlorophyllin level in lymphocytes

Abstract

This study raises the question of whether it is possible to determine the appearance of sodium-copper chlorophyllin in lymphocytes. To answer this question, the content of chlorophyllin was determined in lymphocyte lysate previously incubated in a medium containing 300 uM of copper chlorophyllin. Significant amounts of chlorophyllin were observed in the lysate, thus, suggesting that chlorophyllin is able to enter cells. However, the question remains as to whether chlorophyllin can pass through the nuclear membrane. Based on our own data and information obtained from the scientific literature, it can be concluded that the passage of chlorophyllin through the nuclear membrane happens at a much slower rate than through the plasmalemma.