Abstract
Non-steroidal anti-inflammatory drugs are the common and novel category of drugs which are widely used for the treatment of pain, inflammation and fever. NSAIDs inhibit the synthesis prostaglandins by the action on the cyclooxygenase enzymes. This review revealed the analytical method reported in literature for the determination of zaltoprofen, loxoprofen, ketoprofen, and flurbiprofen in pharmaceutical formulations in alone and combinations with other drugs. The comparison of twenty one analytical methods, including HPLC, UV-Spectrophotometry, and bioanalytical procedures, is most effectively illustrated in this comprehensive overview. To produce trustworthy data for regulatory filings, analytical development needs to be tested. A revolution in human health was brought about by the development of pharmaceuticals.
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