Abstract

N. Kawai, A. Miwa and T. Abe. Specific antagonism of the glutamate receptor by an extract from the venom of the spider Araneus ventricosus. Toxicon 21, 439 – 441, 1983. — A venom sac extract selectively and irreversibly suppressed excitatory postsynaptic potentials in the lobster neuromuscular junction without affecting inhibitory postsynaptic potentials. Glutamate-induced depolarization of the postsynaptic membrane was blocked by the venom extract, whereas membrane depolarization by aspartate was unaffected.

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