Abstract
Background: Hand, foot and mouth disease (HFMD) is a widespread pediatric disease caused primarily by human enterovirus 71 (EV-A71) and Coxsackievirus A16 (CV-A16). Over the past two decades, our understanding of HFMD has greatly improved and it has received significant attention. This study reports a systematic review of spatio-temporal analysis of HFMD. Materials and Methods: Systematic and comprehensive searches were conducted in the PubMed, Scopus, Web of Science, and Google Scholar. Four different issues related this issue are presented under four sub-sections; including the analysis of spatial-temporal clustering, hotspot and coldspot, spatial-temporal heterogeneity and risk factors Results: It was found from 64 articles that spatio-temporal analysis can effectively support the study of HFMD such as understanding of spatial patterns, hotspot, the spread and affecting factors. Conclusion: The spatial-temporal analysis can provide important information and contribute to development of effective measurements to control and prevent its transmission. The study contributes to current research on the spread and affecting factor of HFMD. Keywords: Spatio-temporal analysis, Spatial autocorrelation, GIS, Spatial patterns, Hand, foot and mouth disease, Review.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Science and Healthcare Research
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
