Spatial Compounding Technique to Obtain Rotation Elastogram: A Feasibility Study

Abstract

The perception of stiffness and slipperiness of a breast mass on palpation is used by physicians to assess the level of suspicion of a lesion as being malignant or benign. However, most current ultrasound elastography imaging methods provide only stiffness-related information. There is no existing approach that provides information about the local rigid body rotation undergone by only a loosely bonded, asymmetrically oriented lesion subjected to a small quasi-static compression. The inherent poor lateral resolution in ultrasound imaging poses a limitation in estimating the local rigid body rotation. Several techniques have been reported in the literature to improve the lateral resolution in ultrasound imaging, and among them is spatial compounding. In this study, we explore the feasibility of obtaining better-quality rotation elastograms with spatial compounding through simulations using Field II and experiments on tissue-mimicking phantoms. The phantom was subjected to axial compression (∼1%–2%) from the top, and the angular axial and lateral displacement estimates were obtained using a multilevel 2-D displacement tracking algorithm at different insonification angles. A rotation elastogram (RE) was obtained by taking half of the difference between the lateral gradient of the axial displacement estimates and the axial gradient of the lateral displacement estimates. Contrast-to-noise ratio was used to quantify the improvements in quality of RE. Contrast-to-noise ratio values were calculated by varying the maximum steering angle and the incremental angle, and its effects on RE quality were evaluated. Both simulation and experimental results corroborated and indicated a significant improvement in the quality of RE using compounding technique.