Spatial and temporal evolution of liver cancer incidence

Abstract

Liver cancer has become a global public health problem and is the fourth leading cause of death and the sixth most common cancer worldwide. The article comprehensively constructed a system of indicators to measure the level of liver cancer incidence from three aspects: economy, diet, and health indicators, and analyzed the influencing factors of liver cancer incidence in 204 countries and regions in the world and the geographical characteristics of the level by using multivariate statistical analyses such as the coefficient of variation method and geodetector. The study shows that (1) the incidence rate of liver cancer is lower in countries with higher GDP levels and urbanized population rates. (2) The combination of caloric intake and protein intake had the largest interaction effect on liver cancer incidence. (3) Excessive fat and protein intake will increase the burden on the liver and cause an increase in the incidence of liver cancer.