SP6.11 Histological Findings in Routine Gallbladder Specimen for Benign Disease

Abstract

Abstract Aim Gallbladder is one of the most frequently analysed specimens in pathology departments. Non-selective approach is followed by most surgeons with its associated cost and time implications. This study aims to highlight the incidence of histological abnormalities that can be found in the specimen sent following cholecystectomy for benign pathology. Methods Retrospective review of histology reports over 10 years period (2010-2019) in district general hospital performed. Non-selective approach used by our surgeons to send specimen following cholecystectomy. Emergency and elective cholecystectomy in adult patients included. Any suspicious diagnosis preoperatively excluded. Histological diagnosis using SNOMED coding from pathology department used. Results 6020 Histology reports reviewed. Chronic cholecystitis reported in 4113 case (68%), acute cholecystitis seen in 1587 cases (30%). Only 120 reports (2%) described abnormal histology which includes neoplastic and non-neoplastic lesions. Neoplastic lesions found in 90 cases: cancer=10 cases (0.16%) and dysplasia in 80 cases: high grade= 4 cases (0.06%), low grade= 73 (1.2%) and metaplasia in 3 cases (0.04%). Non-neoplastic lesions seen in 30 cases: adenoma= 7 (0.11%), polyp= 13 (0.21%), lipoma=2 (0.03%), cysts=2 (0.03%) and granulomatous cholecystitis in 6 cases (0.09%). Conclusion This study demonstrates the frequency of abnormal histology seen in routing specimen. This is an important information to quote during the consent process and also may help in adopting a selective approach for cholecystectomy performed for benign disease.