Abstract
SummaryAfter stimulation in vivo with heat-killed Staphylococcus aureus, rat peritoneal granulocytes and macrophages produced leukocytic endogenous mediator (LEM). When this LEM was injected into normal rats, it lowered plasma iron and zinc concentrations and markedly increased blood neutrophils. Incubation of macrophages. blood leukocytes, or Kupffer cells with S. aureus in tissue culture media and rat plasma in vitro gave low yields of LEM. Further evidence was presented to show that serum taken from rats 4 hr after an ip injection of Diplococcus pneumoniae contained LEM.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.