Sources, gastrointestinal absorption and stereo-selective and tissue-specific accumulation of Dechlorane Plus (DP) in chicken

Abstract

Dechlorane Plus (DP) isomers, along with two dechlorinated metabolites were measured in environmental matrices, chyme and digestive tract contents and tissues of chicken from an e-waste recycling site located in South China. Soil is proved to be the main source of DP in chicken rather than food because soil contributes more than 94% of total DP in chyme. In the gastrointestinal tract absorption processes, no selective absorption was observed for DP isomers during the ingestion processes. The tissue distribution of DP isomers in chicken exhibits complicated characteristics. The lipid contents in tissues are the main factors in the tissue distribution of DP, while the different blood perfusion state and the different tissue functions also seem to influence the tissue distribution of DP. The fat, brain, and liver exhibit higher fanti values (0.65, 0.64, and 0.64) than the other tissues (0.54–0.59). The elevated fanti values of DP from the contamination source (0.52 in soil) to chicken suggest stereoselective bioaccumulation of anti-DP in chicken. The similar ratios of anti-Cl11-DP to anti-DP between soil and chicken imply that anti-Cl11-DP mainly derives from the uptake from environment rather than in vivo dechlorination.