Abstract
Background and Aims : Cardiac shockwave therapy is a novel, noninvasive approach that has been shown to ameliorate the myocardial ischemia and improve cardiac function. Cardiac shockwave therapy is a potential and effective remedy to promote revascularization in the ischemic myocardium of patients with refractory coronary heart disease. The technique is both safe and non-invasive.; however, the underlying molecular mechanism remains unclear. In this study, we developed an sono- shock wave combination therapy system and investigated its effectiveness on myocardial angiogenesis in the hamsters accompanied by PESDA (Perfluorocarbon- Exposed Sonicated Dextrose Albumin) microbubbles administration.
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