Abstract
Two mammalian mitochondrial transcription factors (TFB1M and TFB2M) share homology with universally expressed dimethyltransferases that modify conserved adenines in the small ribosomal subunit rRNA. Work in this issue (Metodiev et al., 2009) shows that loss of TFB1M abolishes mitochondrial ribosome assembly without affecting mitochondrial transcription.
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