Abstract
Purpose: To identify some risk factors for hospital infections in the ICU, Vietnam National Children’s Hospital in 2018-2019.
 Method: A prospective cohort study was conducted.
 Results: Malnutrition grade II or higher, PRISM > 10, ≥ 3 invasive intervention, use of H2-receptor antagonists and intravenous feeding were risk factors for nosocomial infections. Endotracheal intubation, intubation for > 5 days, re-intubation, and aspiration of vomit were risk factors for nosocomial pneumonia. Intravenous exposure, 3 or more IV lines, and central venous catheterization were risk factors for sepsis. Gastrointestinal surgery, surgery time > 2 hours, postoperative drainage, drainage time > 5 days and no prophylactic antibiotics were risk factors for wound infection. Urinary retention and urinary flow > 3 days were risk factors for urinary tract infections.
 Conclusion: Nosocomial infections with grade II or higher malnutrition and 3 invasive interventions, the use of H2-receptor resistance and intravenous nutrition associated with nosocomial infections. Pneumonia, urinary tract infections, and sepsis are high risk factors for nosocomial infections.
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