Risk factors of nosocomial infection in patients with postpartum hemorrhage and the analysis of common pathogens

Abstract

Objective To analyze the risk factors of nosocomial infection in patients with postpartum hemorrhage and the distribution of common pathogens, and to provide basis for reducing the infection incidence in patients with postpartum hemorrhage. Methods 134 patients with postpartum hemorrhage admitted from Jan. 2011 to Dec. 2013 in our hospital were studied. The incidence of infection was observed in patients, and clinical data of patients were analyzed by univariate and multivariate Logistic regression. The risk factors of infection were was observed and blood samples from infected patients were analyzed to observe the distribution of common pathogens. Results Among the 134 cases, 42 cases had puerperal infection, accounting for 31.34%, and 4 cases had obstetric wound infection, accounting for 2.99%. Univariate analysis showed that advanced maternal age, high-risk pregnant women, midwifery or cesarean section, invasive treatment, and long hospital stay were risk factors for infection. Logistic regression analysis showed that high-risk pregnant women, midwifery or cesarean section, invasive treatment, and long hospital stay were independent risk factors for infection. 52 pathogens were detected from 46 patients. 28 Gram-positive bacteria were identified, of which 15 cases of were staphylococcus aureus, accounting for 28.85% and 22 Gram-negative bacteria were identified, of which 11 were escherichia coli, accounting for 21.15%. Conclusions Gram-positive bacteria are the majority in patients with postpartum hemorrhage and infection. High-risk pregnant women, midwifery or cesarean section, invasive treatment, and long hospital stay are independent risk factors for infection. Puerperal infection also need to be noted when postpartum hemorrhage occurs. Key words: Postpartum hemorrhage; Nosocomial infection; Pathogens