Abstract
The following hypotheses are suggested concerning the possible roles of sympathomimetic amines in psychiatric conditions: 1. Isuprel, or a similar substance, may be an important chemical mediator in anxiety. 2. Another amine, possibly nor-epinephrine, may be an important chemical mediator in aggression and hostility. 3. When a patient experiences approximately equal quantities of hostility and anxiety, equipotent concentrations of Isuprel and the other amine may be liberated, producing depression, by a mechanism similar to that whereby a mixture of 2 amines depresses the isolated mammalian auricle, although either amine alone has a stimulant action. An additional possibility suggested by continuing studies in this field is that the depression of rate and force observed with the mixture of amines is produced by an intermediate metabolite, formed within 1 or 2 minutes.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
