Abstract
During the past five years we have been engaged in a study of the organic functions in schizophrenia. During the course of the work it has become rather apparent that subjects of this disorder are characterized by a generalized hypometabolism. The depression is manifested in a variety of functions directly or indirectly related to the oxygen metabolism. Among other characteristic features are secondary anemia, low blood pressure, reduced body temperature, and sub-normal oxygen consumption rate. These findings, among others, are suggestive of a condition of chronic, underfunction of the adrenal glands. Convincing differential diagnostic indications of that condition, however, have not been seen. On a purely empirical basis, we have made various attempts to normalize the organic functions of the patients by the use of various sorts of preparations of adrenal cortex. In a previous publication (1) the negative results obtained in a small series of patients from simple desiccated glandular material were report...
Published Version
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