Abstract
Biological and biochemical processes are affected by the partial or complete replacement of solvent protium oxide (H2O) by deuterium oxide (D2O) (1) Although some very simple organisms (certain algae, bacteria, etc.) have survived complete replacement of protium by deuterium, differences in morphology and metabolism are very apparent. Not surprisingly, deuterium substitution affects virtually all aspects of metabolism and physiological function. Higher plants, after experiencing impaired chlorophyll synthesis and inhibition of cell division, will cease to grow after ~ 70% D exchange Mammals (unable to survive much more than 25% D incorporation) show evidence of severe difficulty with protein synthesis, decreased enzyme levels, decreased erythrocyte production, impaired carbohydrate metabolism, hormone imbalance, central nervous system disturbance, difficulty with mitosis, and increasingly impaired reproductive capability. Most of these consequences are directly or indirectly attributable to changes in the rates of biochemical reactions.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call