Abstract
The solubilities of l-glutamine in mixed solvents (ethanol+water, acetone+water) were determined at temperatures between 278K and 313K. The solubilities of l-glutamine in mixed solvents (water+ethanol, water+acetone) are a function of temperature, increasing with an increase in temperature. Pure water has a high dissolving power. The experimental data were correlated with the Apelblat model. The calculated values of Apelblat model were found to show a fine representation of the experimental data. Then the dissolution enthalpy and entropy of l-glutamine were predicted from the solubility data using van’t Hoff equation. The dissolution enthalpy and entropy of l-glutamine in water predicted from the solubility data is less than that in mixed solvents.
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