Abstract
We report on a 23-year-old patient with a benign granular cell tumor on the left shoulder and a thrombosed angioma on the right lower leg. First both tumors were clinically suspected to be a malignant melanoma with a giant skin metastasis. Only the histological and immunohistochemical examination resulted in the surprising diagnosis of a granular cell tumor. Granular cell tumors are rare and mostly benign. About the origin of the typical granular cells there is still a controversial discussion: The most widely accepted theory postulates an origin from the peripheral nerve system. Immunohistochemical studies seem to support this theory, but there are also contradictory results.
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