Abstract
A pulmonary nodule is a common incidental finding on chest imaging, which includes a wide variety of differential diagnosis. Pulmonary hyalinising granuloma is a rare disease aetiology of pulmonary nodule(s). We report a 74-year-old female who was referred to the respiratory clinic with incidental finding of a solitary pulmonary nodule on chest X-ray. CT confirmed the presence of a 1.2 cm solitary pulmonary nodule in the left upper lobe with no lymphadenopathy. The patient underwent wedge resection, and histopathological examination of the lesion confirmed pulmonary hyalinising granuloma. In most previously reported cases, patients had multiple lesions on chest radiography. Solitary pulmonary lesion is an uncommon presentation of this clinical entity and only a few cases have been reported in the literature.
Highlights
Pulmonary hyalinising granuloma (PHG) is a rare condition, presenting more often as multiple pulmonary nodules. It is characterized by fibrosing nodules, consisting of central whorled deposits of lamellar collagen
DIFFERENTIAL DIAGNOSIS PHG is included in the differential diagnosis of diseases such as infectious granulomatous diseases, non-infectious granulomatous diseases, amyloidosis and rheumatoid lung involvement
PHG was first described in 1977.1 The mean age of presentation is 45, with an age range of 15–77.1,2 There is no gender or racial predilection.[2]
Summary
BACKGROUND Pulmonary hyalinising granuloma (PHG) is a rare condition, presenting more often as multiple pulmonary nodules. A biopsy is required to establish the diagnosis of PHG. Presentation as a solitary nodule is rare. CASE PRESENTATION A 74-year-old female was referred to the respiratory clinic with incidental finding of a pulmonary nodule on chest Xray.
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