Solitary fibrous tumor arising from pericardium Case report of a rare entity

Abstract

Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm mainly originated in the pleural cavity. We report here an unusual case of a large SFT arising from the pericardium. A 40 year female with complaints of left sided chest pain was admitted to our hospital with a diagnosis of pericardial mass. CT showed a 11x7 cm mass arising from pericardium showing enhancement and peripheral calcification. Excised mass showed a grey brown well circumscribed nodular mass measuring 8x6x5cm along with attached lobe of lung measuring 6x4x3 cm. Microscopic examination showed a predominant population of monotonous bland looking ovoid to spindle cells arranged in patternless pattern or interlacing bundles with areas of necrosis , hemorrhage and myxoid change, mild nuclear atypia and no mitotic activity. Immunohistochemistry revealed that the tumor cells were positive for CD34, BCL-2, Vimentin and Desmin (focally) and negative for EMA, SMA and Calretinin. Based on histomorphology and immunohistochemistry, the final diagnosis of solitary fibrous tumor was made.