Abstract
Secondary caries caused by plaque accumulation at the edge of crown restorations is still a significant reason for crown restoration treatment failures. To prevent secondary caries, it is urgent to develop dental crown restorative materials with good antibacterial ability and mechanically stable properties. In this work, functionalized dental crown restorations were successfully prepared by doping the human trace element Zn into sodium aluminum silicate ceramics (NAS/Zn). The results demonstrated that the NAS/Zn composite ceramics killed Streptococcus mutans (S. mutans) effectively. The Zn ions released by NAS/Zn composite ceramics disrupted the bacterial membrane integrity and DNA proliferation, promoted the outflow of protein, and eventually led to bacterial death. Most notably, NAS/Zn composite ceramics exhibited excellent biocompatibility. This study will provide a new strategy to prevent the occurrence of secondary caries via the construction of dental crown restorative materials.
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