Abstract
Objective: This study aimed to explore sociodemographic determinants of therapy adherence in warfarin patients.
 Methods: A cross-sectional study using a newly developed and validated research tool was conducted in warfarin patients. Data was collected by convenience sampling method. Descriptive, comparative, and inferential statistics were used by Statistical Package for the Social Sciences (SPSS) ver. 24 to determine the sociodemographic determinants of warfarin knowledge in warfarin patients.
 Results: Out of the total 319 warfarin patients, the majority of the studied warfarin patients were females than males (n=221, 69.3%, and n=98, 30.7% respectively). In univariate analysis, statistically non-significant differences (p >0.05) in age, work, comorbidities and warfarin usage in different diseases. In multivariate analysis, significant differences (p <0.05) were observed in gender and marital status of the studied warfarin patients.
 Conclusion: These results indicated that education, warfarin usage, and warfarin therapy duration were the pure determinants of HRQoL among the studied cohort of the warfarin patients.
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