Abstract
In this chapter, the design, fabrication and performance of smart microcapsules with pH-responsive chitosan hydrogel membranes are introduced. The pH-responsive microcapsules with crosslinked chitosan membranes are fabricated with a microfluidic approach using monodisperse O/W/O emulsions as templates to form a crosslinked chitosan membrane at the inner O/W interface via interfacial crosslinking reaction between chitosan and terephthalaldehyde. The chitosan microcapsule membranes show acid-induced pH-responsive swelling and decomposing behavior. Such monodisperse polysaccharide microcapsules with pH-responsive chitosan hydrogel membranes could serve as promising candidates for pH-responsive drug delivery systems.KeywordsDouble EmulsionChitosan HydrogelHydrogel MembraneCapsule MembraneMicrofluidic ApproachThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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