Abstract
This chapter highlights recent synthetic reactions catalyzed by small organic molecules, classified into two main categories, namely: Bronsted and Lewis Acid and Bronsted and Lewis Base Catalysis. Small organic molecule catalyzed reactions continue to be of key interest in modern synthetic chemistry. Many organocatalysis reactions have demonstrated to be a powerful protocol in generating selectively several bonds and stereogenic centers in a one-pot operation. Many theoretical studies, including the computational prediction of stereoselectivities and reaction mechanism were also reported. Indisputably, the booming subject of the advanced organocatalysis reactions will continue to thrive for decades. In order to gain practical aspects into the subject for creating the more efficient methodologies, an update and brief overview in this subject is essential. The chapter provides some of the recent advances of this subject and the contents were categorized by the types of organocatalysts. Keywords: Lewis Base Catalysis; modern synthetic chemistry; organocatalysis; stereoselectivity; synthetic reactions
Published Version
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