Abstract
We performed a feasibility study of Small angle X-ray scattering imaging under the condition of X-ray bright field imaging by Laue crystal diffraction optics of X-ray dark-field imaging that works as an angular analysis. Collagen in chicken tibia containing abundant soft fibrous tissue was chosen as a specimen. In traditional Small angle X-ray scattering optical system, we can derive the structure information of sample by calculating q value which is available from a scattering pattern. Thus it is usually necessary to conduct a 2D scan in order to obtain scattering image. In this paper it is described by a method by which not only small angle X-ray scattering imaging is available directly but also bright-field imaging and dark-field imaging can be obtained at the same time. As the first step, the feasibility of the imaging method should be confirmed by taking pictures of the samples with known periodic length. The preliminary test showed that the collgan’s lattice spacing d is 65.1 nm that was also taken photos by scanning electron microscopy. By rotating Laue angular analyzer by 112 arcseconds small angle X-ray scattering image appeared in bright-field.
Highlights
When the X-rays pass through the object, three kinds of interactions mainly occur such as absorption, refraction, scattering
We performed a feasibility study of small angle X-ray scattering imaging under the condition of X-ray bright field imaging by Laue crystal diffraction optics of X-ray dark-field imaging that works as an angular analysis
We study a new method to take a photo of small angle scattering imaging by rotating the Laue angular analyzer to exact scattering part by X-ray dark-field imaging (XDFI) optical system
Summary
When the X-rays pass through the object, three kinds of interactions mainly occur such as absorption, refraction, scattering (small angle scattering and Compton scattering). Refraction phase contrast imaging has two advantages over absorption contrast: it can provide high contrast in soft tissue including articular cartilage and it can relatively suppress radiation dose. This X-ray imaging technology is applicable to medical diagnosis, performance evaluation of biomaterials and so on. XDFI has got success of viewing a variety of internal organs such as breast cancer, articular cartilages of finger, knee and shoulder, eye ball and blood cells such as iliac artery and coronary artery without staining with contrast agent in pathological way [5] [6] This has brought us an image of scattering quite different from absorption based images. It is expected that revealing the genesis of soft tissue lesions by visualization of subtle structures and becoming a useful tool for medical imaging in future
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