Abstract
Abstract We describe the case of an architect, MF, who in his fifties presented a 10-year progressive cognitive deterioration similar to that recently classified as semantic dementia. For a long period general intelligence, non-lexical aspects of language, memory and pre-semantic stages of visual perception were spared. MF showed a lexical-semantic deficit that was more severe for living things, famous people and architectural knowledge and concerned both visual and encyclopaedic information. Visual and encyclopaedic knowledge about tools, vehicles and furniture was completely spared for a long time. On MRI, our patient presented severe atrophy of the temporal lobes, that most severely affected the right side and also involved basal neocortex, hippocampus and parahippocampal gyri.
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