Abstract

To elucidate age-related changes of the first septal perforator branch (FSB), the authors investigated age-related changes of elements in the FSBs by direct chemical analysis. In addition, the effects of different arterial sizes and genders on element accumulation were investigated in the FSBs. Sixty-two formalin-fixed adult Thai hearts were used and the FSBs were carefully dissected in the hearts. After the arteries were incinerated with nitric acid and perchloric acid, element contents were determined by inductively coupled plasma-atomic emission spectrometry.

Highlights

  • The conduction system of the heart is supplied by the sinoatrial nodal (SAN) artery, the atrioventricular nodal (AVN) artery, the first septal perforator branch (FSB) of the left anterior descending artery (LAD), and the posterior descending branch of the right coronary artery (RCA)

  • It is well known that a high accumulation of Ca and P occurs in the proximal sites of the LAD, left coronary artery (LCA), RCA, and left circumflex artery (LCX) with aging [1,2,3]

  • Wasilewski et al [4] investigated calcification of the LAD including the FSB by multi-slice computed tomography and revealed that calcification was most frequently located in the LAD in proximity to the FSB origin, but it was not located in the FSB

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Summary

Introduction

The conduction system of the heart is supplied by the sinoatrial nodal (SAN) artery, the atrioventricular nodal (AVN) artery, the first septal perforator branch (FSB) of the left anterior descending artery (LAD), and the posterior descending branch of the right coronary artery (RCA). These arteries ensure adequate blood supply to maintain the electrical properties in the heart. It is well known that a high accumulation of Ca and P occurs in the proximal sites of the LAD, left coronary artery (LCA), RCA, and left circumflex artery (LCX) with aging [1,2,3].

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