Abstract
Background: The impaired sleep quality of acutely ill patients has been reported in several studies. The aim of our study was to evaluate the sleep patterns of chronically ventilated patients and to determine whether their sleep quality is influenced by the modes of mechanical ventilation. Methods: We performed polysomnography on 5 chronic ventilator-dependent patients for about 24 hours, in different assist-control ventilation and pressure support modes, and then recorded the sleep architecture and latency of the different sleep stages. Results: The mean total sleep time was within normal range, but the results of other sleep stage parameters, such as the markedly increased stage I and stage 2 non-rapid eye movement sleep, severely reduced slow wave sleep and rapid eye movement sleep period, and sleep fragmentation, were similar to those of the previous reports of acutely ill patients. The sleep profile showed no significant difference between the effects of the assist-control mode and the pressure support mode. Conclusion: Chronically ventilated patients have similar sleep disruption and as severe sleep fragmentation as acutely ill patients, except for the total sleep time. There is no evidence to prove whether sleep quality is influenced by different mechanical ventilation modes, such as the assist-control mode and the pressure support mode.
Published Version
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