Abstract
Subjective sleep complaints have been reported in up to 80% of patients with end stage renal disease (ESRD). In these patients, sleep disturbances manifesting as insomnia, sleep apnea syndrome, restless leg syndrome (RLS), periodic limb movement disorder and excessive daytime sleepiness (EDS) have been frequently reported. Moreover, studies about the role of dialysis shift on sleep abnormalities, morbidity and mortality are still scarce. The aim of this study was to investigate the influence of dialysis shift on the quality of sleep and sleep abnormalities in patients with ESRD. We studied one hundred consecutive patients from a dialysis center. Quality of sleep was assessed by the Pittsburgh Sleep Quality Index and subjective EDS by the Epworth Sleepiness Scale. Restless leg syndrome was diagnosed using the four minimum criteria defined by the International Restless Legs Syndrome Study Group. Clinical and laboratory parameters were obtained by interview and chart review. Adequacy of dialysis was evaluated by the Kt/V index. Poor quality sleep (PSQI>6) was found in 75% of cases and was associated with RLS (p=0.004) and with snoring (p=0.016). EDS (ESS>10) was present in 28% of cases. Patients with EDS (1.33+/-0.29) had lower values of the Kt/v index (P=0.01) than those without EDS (1.52+/-0.32). RLS was present in 48% of cases. Irrespective of dialysis shift, poor quality sleep, EDS and RLS were not different among patients. Poor quality sleep, EDS and RLS were common and not related to dialysis shift.
Highlights
Subjective sleep complaints have been reported in up to 80%
In addition to poor sleep quality, reduced life expectancy has been associated to presence of restless legs syndrome (RLS) in end stage renal disease (ESRD) 1,5
RLS was detected in 48% of patients and was not associated with dialysis shift (OR= 1.06, 95% CI= 0.62-1.81)
Summary
Of patients with end stage renal disease (ESRD). Sleep disturbances, such as insomnia, sleep apnea syndrome (SAS), restless legs syndrome (RLS), periodic limb movements (PLM) disorder and excessive daytime sleepiness (EDS) have been frequently reported in these patients. These alterations have been described as having a negative effect on quality of life and functional status[1]. Long term studies about repercussion of these abnormalities on morbidity and mortality have yet to be performed. Studies about the role of dialysis shift on sleep abnormalities, morbidity and mortality are still scarce[2,3]. Despite the fact that symptomatic treatment for RLS is available, in their majority patients remain non-diagnosed and untreated[6]
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