Abstract
Alzheimer’s disease (AD), one of the leading causes of dementia worldwide, is commonly accompanied by behavioral and psychopathological disorders. The earliest observed symptoms of AD include sleep disorders, the incidence of which varies from 25 to 60%. Sleep problems and sleep disorders can develop as one of the symptoms accompanying cognitive impairment, but can also be associated with an increased risk of cognitive decline and with a higher risk of dementia. Anti-dementia therapy is of great importance in preventing and treating sleep disorders in patients with AD. Akatinol memantine is one of the drugs with proven efficacy in such patients.
Highlights
Alzheimer’s disease (AD), one of the leading causes of dementia worldwide, is commonly accompanied by behavioral and psychopathological disorders
Anti-dementia therapy is of great importance in preventing and treating sleep disorders in patients with AD
Нарушения сна при болезнью Альцгеймера (БА) Нарушения сна, по-видимому, относятся к самым ранним наблюдаемым симптомам БА, появляющимся задолго до диагностики когнитивного снижения и деменции [3]
Summary
Alzheimer’s disease (AD), one of the leading causes of dementia worldwide, is commonly accompanied by behavioral and psychopathological disorders. Распространенность нарушения сна у пациентов с БА, по данным разных исследований, колеблется от 25 до 60%, что делает их весьма частым проявлением БА. Расстройства сна при БА могут настолько существенно влиять на поведенческие, функциональные и когнитивные способности пациентов, что становятся основным фактором, определяющим необходимость постороннего ухода [7].
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