Skull Base Chordoma: About Two Cases and Literature Review

Abstract

Skull base chordomas are rare primitive bone tumors developed at the expense of remnants of the embryonic notochord at the level of the clivus, characterized by invasive behavior at the local level with possibility of extension to neighbouring organs. The deep localization of these tumors and their proximity to the structures of the base of the skull round a carcinological resection difficult if not impossible. Radiation therapy, both adjuvant to surgery and exclusive, is a therapeutic approach to improve local control and quality of life for patients. We present two cases of patients followed for skull base chordoma treated with exclusive radiotherapy.