Abstract

This article provides an overview of the progress made in skin imaging using two emerging imaging modalities, optical coherence tomography (OCT) and photoacoustic imaging (PAI). Over recent years, these technologies have significantly advanced our understanding of skin structure and function, offering non-invasive and high-resolution insights previously unattainable. The review begins by briefly describing the fundamental principles of how OCT and PAI capture images. It then explores the evolving applications of OCT in dermatology, ranging from diagnosing skin disorders to monitoring treatment responses. This article continues by briefly describing the capabilities of PAI imaging, and how PAI has been used for melanoma and non-melanoma skin cancer detection and characterization, vascular imaging, and more. The third section describes the development of multimodal skin imaging systems that include OCT, PAI, or both modes. A comparative analysis between OCT and PAI is presented, elucidating their respective strengths, limitations, and synergies in the context of skin imaging.

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