Abstract
BackgroundWith an increasing number of patients, those who are facing a lot of skin-related complaints, often referred to as skin of pigmentation patients, are on the rise. Among all the most common complaints in patients with skin of color is hyperpigmentation. So, there is need of herbal formulation for treatment of hyperpigmentation.Main bodyThis review article addresses the different types of hyperpigmentation, causes, and its treatment with herbs for the management of the skin hyperpigmentation. As uneven pigmentation of skin or hyperpigmentation is a common skin condition, which occurs when the skin produces more melanin. This can make spots or patches of skin appear darker than surrounding areas. Some forms of hyperpigmentation with post-inflammatory, melasma, and sun spots are more likely to affect areas of face, arms, and legs due to sun exposure and injury. Although the availability of multiple treatments for the condition which leads to some adverse effects, hyperpigmentation continues to present skin care management challenges for dermatologists.ConclusionSome plants and phytoconstituents, e.g., Azadirachta indica, Glycyrrhiza glabra, Panax ginseng and genistein, ellagic acids, quercetin, are very useful in herbal cosmetic as anti-hyperpigmentry agents in cosmetic industries. Some of flavonoids and triterpenoids present in plants also show their effect as antioxidant and skin whitening agents. It is expected that this review will compile and improve the existing knowledge on the potential utilization of herbs for the treatment of skin hyperpigmentation.
Highlights
Type of skin hyperpigmentation Post-inflammatory hyperpigmentation It is the acquired hypermelanosis after the skin inflammation or injury that can occur in all skin types
Melanin is an important pigment in skin hyperpigmentation which is produced by the process called melanogenesis
In this review, we discussed many of herbs and phytoconstituent which are used as tyrosinase inhibitor and as skin whitening agents
Summary
We discussed many of herbs and phytoconstituent which are used as tyrosinase inhibitor and as skin whitening agents. Melanin is a pigment present in skin which is responsible for the skin color in plants and mammals. Synthesis of melanin depends mainly on tyrosinase enzyme. It convert L-tyrosine in LDOPA and L-DOPA to dopaquinone by which melanin is produced in the epidermis layer of skin and affect the skin color. Plants like Azadiracta indica, Glycyrrhiza glabra, Panax ginseng and genistein, ellagic acids, quercetin, and many other phytoconstituents which are used in herbal cosmetic as anti-hyperpigmentry agents in cosmetic industries. Some of flavonoids and triterpenoids present in these herbs show their effect as antioxidant and skin whitening agents
Published Version
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