Abstract

The concentration of phospholipids and lecithin, and the composition of the lecithin fatty acids were determined in the human gastrocnemius muscle of males from early foetal stage to middle age. The concentrations of phospholipids and lecithin were rather constant apart from a slight increase in early childhood. In 8 normal adults total phospholipids and lecithin constituted 11.6 (S.D. ± 0.7) and 5.4 (S.D. ± 0.3) μmoles/g wet tissue weight, respectively. The fatty acid composition of skeletal muscle lecithin varied considerably with age, the linoleic acid concentration increasing from 4% in the beginning of the second trimester of gestation to 40% at the age of one year. In adults linoleic acid constituted about 40% by weight. The concentration of fatty acids of the linolenic acid series was very low.

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