Six-year telomere shortening is associated with increased incidence of subclinical carotid vascular damage and cardiovascular prognosis

A Baragetti,J Palmen,K Garlaschelli,L Grigore,S Humpries,A Catapano,P Talmud,G Norata

doi:10.1016/j.atherosclerosis.2014.05.016

Six-year telomere shortening is associated with increased incidence of subclinical carotid vascular damage and cardiovascular prognosis

A Baragetti, J Palmen + Show 6 more

https://doi.org/10.1016/j.atherosclerosis.2014.05.016

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Journal: Atherosclerosis

Publication Date: Jul 10, 2014

Affiliation: University of Milan, University College London, Ospedale Bassini

#Cellular Replicative Capacity #Leukocytes Telomere Length + Show 8 more

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Abstract

Objectives: Leukocytes Telomere Length (LTL) is an important determinant of telomere function and cellular replicative capacity. Recent findings support an association of LTL with age-related diseases, including coronary heart disease (CHD). The association between prospective telomere shortening (TS) and the progression of common carotid intima-media thickness (CCA-IMT) is unknown.

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