Abstract
Recent positive clinical results in cancer immunotherapy point to the potential of immune-based strategies to provide effective treatment of a variety of cancers. In some patients, the responses to cancer immunotherapy are durable, dramatically extending survival. Extensive research efforts are being made to identify and validate biomarkers that can help identify subsets of cancer patients that will benefit most from these novel immunotherapies. In addition to the clear advantage of such predictive biomarkers, immune biomarkers are playing an important role in the development, clinical evaluation and monitoring of cancer immunotherapies. This Cancer Immunotherapy Resource Document, prepared by the Society for Immunotherapy of Cancer (SITC, formerly the International Society for Biological Therapy of Cancer, iSBTc), provides key references and online resources relevant to the discovery, evaluation and clinical application of immune biomarkers. These key resources were identified by experts in the field who are actively pursuing research in biomarker identification and validation. This organized collection of the most useful references, online resources and tools serves as a compass to guide discovery of biomarkers essential to advancing novel cancer immunotherapies.
Highlights
Immunotherapy has emerged as an important treatment strategy for patients with cancer
The society has long recognized the importance of biomarkers for cancer immunotherapy, which has been the focus of a number of Society for Immunotherapy of Cancer (SITC)/iSBTc symposia and workshops [1-5], and has published recommendations [6] and summaries [7-10]
The results show a complementary sequence, oligo length, GC content, melting temperature, extinction coefficient, molecular weight, μg/OD, and nmoles/OD
Summary
Immunotherapy has emerged as an important treatment strategy for patients with cancer. To support the efforts of investigators involved in research to identify and validate biomarkers for cancer immunotherapy, the authors and members of the SITC Biomarkers Taskforce have identified key biomarker references and online resources and organized these into this SITC/iSBTc Cancer Immunotherapy Biomarkers Resource Document. This resource document is divided into two sections: Part I: Immunotherapy Biomarker References; and Part II: High Throughput and New Technologies for Biomarker Discovery: Arrays, Platforms, Tools for The Bench and Online Resources. While many important references and resources in the field are included in this document, it does not intend to represent an exhaustive list of all relevant publications, products or resources in the growing, and important field of immune biomarkers.
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call