Abstract
20May 2017 SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) IN PAGE FAMILY MEMBER 4(PAGE4) GENE IN MEN WITH BENIGN PROSTATE HYPERPLASIA FROM IRAQ. Linda , F. Abdul-Sattar , Hayder , I. Al-Ameery and Abdulwahid , B. Al- Shaibani. Medical Tools Department, Director of Materials Researches, Ministry of Science and Technology, Baghdad, Iraq. Department of Urology, Al-Yarmook Teaching Hospital, Baghdad, Iraq Medical and Molecular Biotechnology Department, College of Biotechnology, Al-Nahrain University, Baghdad, Iraq.
Highlights
Received: 12 March 2017 Final Accepted: 07 April 2017 Published: May 2017 polymorphisms (SNPs) in PAGE family member 4 (PAGE4) gene in men with benign prostate hyperplasia from Iraq
Results showed that seven polymorphisms were detected in first region of PAGE family member 4 (PAGE4) gene; six of them were substitution polymorphisms while one was addition polymorphism
Among all PAGE genes expressed in the testes of the adult human, PAGE4 is the only member of this family that is expressed in the prostate, It was located on chromosome Xp23.11, it has 5005bp spanning from nucleotide number
Summary
Received: 12 March 2017 Final Accepted: 07 April 2017 Published: May 2017 polymorphisms (SNPs) in PAGE family member 4 (PAGE4) gene in men with benign prostate hyperplasia from Iraq. Results showed that seven polymorphisms were detected in first region of PAGE4 gene; six of them were substitution polymorphisms while one was addition polymorphism. Blood samples were collected from 80 men with benign prostate hyperplasia, with mean age 68.7 years, 10 samples of them with serum prostate specific antigen between 4-10 ng/ml were selected from eighty samples in this study for detection of polymorphisms in first region of PAGE4 gene.
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