Abstract

HighlightsA single-atom catalyst of A–Co–NG is explored for electrochemical uric acid (UA) detection for the first time and realize practical UA monitoring in serum samples.The A–Co–NG sensor demonstrates high performance for UA detection with a wide detection range from 0.4 to 41950 μM and an extremely low detection limit of 33.3 nM.Combination of experimental and theoretical calculation discovers mechanism for the UA oxidation on the single-atom catalyst.

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