Abstract
Single-photon emission computed tomography is a widely used modality based on single-photon detection of radionuclides. However, research still needs to be conducted on further increasing the image contrast. We recently proposed a novel method called double-photon emission coincidence imaging (DPECI) using the coincidence detection of two cascade gamma photons emitted from a radionuclide, such as 111In or 177Lu. Compared with single-photon detection, the coincidence detection of two gamma photons can be used to theoretically identify the position at a single point free of detector rotation and image reconstruction. In this study, we demonstrate DPECI using parallel-hole and slat collimators to improve detection efficiency and verify the feasibility of simultaneous imaging using 67Cu and 111ln.
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