Abstract
Abstract Simultaneous separation of solvent products during fermentation reduces product inhibition and increases reactor productivity. Separation techniques used for simultaneous extraction during ethanol fermentation and butanol-acetone fermentation are reviewed. These techniques can be classified by product removal into gas phase (vacuum fermentation, gas stripping), liquid phase (liquid-liquid extraction, aqueous two-phase system), and solid phase (adsorption). Recent developments in separation techniques use membranes. Membrane separation techniques remove products into gas phase (pervaporation) and into liquid phase (perstraction) using either solid or liquid membranes. Liquid extractants which are nontoxic to microorganisms are required at large quantities because of their poor distribution coefficients. The required amount of solid adsorbents is also large. Gas stripping, pervaporation and perstraction share an advantage of clean product separation. Pervaporation and perstraction can overcome gas-...
Published Version
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