Abstract

For the simultaneous quantification of luliconazole (LUZU) and methyl paraben (MP) in formulation, a straightforward, precise UV spectrophotometric approach was developed and validated. The method was developed using absorbance ratio method. For luliconazole and methyl paraben, the absorbance was measured at 297 nm and 274 nm, respectively. The method was discovered to be linear, sensitive, exact and accurate. ICH guidelines were followed in developing the procedure. Keywords: Q- absorbance ratio method, methyl paraben, luliconazole, and UV spectrophotometric method.

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