Abstract

The re-extraction of penicillin G from the solution of its ion-pair complex with the secondary amine Amberlite LA-2 was mathematically simulated, and the mass transfer coefficients were identified by means of the experimental investigations published in Likidis and Schügerl (1988, Chem. Engng Sci. 43, 27–32) for a bench-scale Karr column, a pulsated perforated plate column and a Kühni column. The longitudinal concentration profiles of penicillin in the aqueous phase in the different types of columns can be described by the same mathematical model and the mass transfer coefficient of the complex/carrier. Only the mass transfer coefficient of the penicillin acid anion differs for the column types.

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