Abstract
This paper describes the simulation of potential actions that occur in nerve cells when given frequency variation as a stimulus. The simulation aims to determine the response of nerve cells to various combinations of currents in this case frequency. The simulation results showed that oscillations occur when the given frequency is 0.045 Hz. While the neural cell response occurs when the frequency between 0.055 Hz-0.065 Hz. The method carried out by the author is to modify the model of Hindmarsh-Rose nerve cells and then simulate it using Matlab programming language. Based on the research that has been done it can be concluded that at a frequency of 0.055 Hz a potential signal of action is formed and oscillates. In the human body, nerve cells and muscle cells are cells that have the ability of excitability (stimulated) because it has membrane potential. Short fluctuations of such cells, serve as electrical signals.
Highlights
Stroke is the second leading cause of death as well as the third leading cause of disability
This paper describes the simulation of potential actions that occur in nerve cells when given frequency variation as a stimulus
International Journal of Biological and Pharmaceutical Sciences Archive, 2021, 01(01), 016–022 Figure 2 signal potential action of nerve cells when the current frequency is given as stimulus= 0.045 Hz Figure 3 signal potential action of nerve cells when the frequency of current given as stimulus= 0.055 Hz
Summary
Stroke is the second leading cause of death as well as the third leading cause of disability. Several types of research related to neural cell models have been widely developed since the 1900s It began with the thinking of Alan Lloyd Hodgkin and Andrew Huxley in 1952 who stated that nerve cell membranes have channels that can be passed by certain ions. The mechanism of impulse propagation presented by both is the potential of nerve cell membranes that play a role to receive impulses in the form of currents from the outside as signals. This signal can activate the mentioned ion channels. This simulation is in addition to knowing that the current can affect the response of nerve cells as well as answer the challenges of the above cases
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