Abstract
AbstractMetal nanoparticles are very valuable products due to their wide range of uses. Among these silver nanoparticles are beneficial products used in many fields, especially in medicine, due to their antibacterial properties. This research aimed to produce silver nanoparticles (Ag NPs) that are both affordable and environmentally friendly. For this purpose, Ag NPs were quickly obtained from domestic waste components of the carrot plant (Daucus carota L.). The UV–vis spectrophotometric, TEM, AFM, FE‐SEM, STEM, EDX, XRD, and DLS analyses were performed to determine the properties of the obtained Ag NPs. It has been found that their surface charge is −21.8 mV, with a maximum absorbance at a wavelength of 421.37 nm, spherical appearance, and an average size distribution of 85.41 nm. The anticancer and antibacterial activities of the produced Ag NPs were investigated by MTT and microdilution. The synthesized Ag NPs showed the most significant antimicrobial effect on Pseudomonas aeruginosa ATCC 27833 with microdilution and low concentration. However, they were also determined to be effective on Bacillus subtilis ATCC 11774 and on Candida albicans ATCC 10231 pathogenic strains. In fact, the effective concentrations of Ag NPs on these strains were significantly lower than the antibiotics used. Furthermore, aside from exhibiting a superior anticancer impact on CaCO‐2 cancer cells, it was established that Ag NPs also had remarkable efficacy in inhibiting U118 and Skov‐3 cancer cells.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call