Silica sulfuric acid as an efficient catalyst for the preparation of 2H-indazolo[2,1-b]phthalazine-triones

Abstract

Silica sulfuric acid as an efficient and reusable heterogeneous catalyst have been used for the preparation of 2 H -indazolo[2,1- b ]phthalazine-1,6,11(13 H )-trione derivatives from the three-component condensation reaction of phthalhydrazide, dimedone, and aromatic aldehydes under solvent-free conditions in good to excellent yields and short reaction times. Silica sulfuric acid as an efficient and reusable heterogeneous catalyst have been used for the preparation of 2 H -indazolo[2,1- b ]phthalazine-1,6,11(13 H )-trione derivatives from the three-component condensation reaction of phthalhydrazide, dimedone, and aromatic aldehydes under solvent-free conditions in good to excellent yields and short reaction times.