Significance of platelet count and platelet indices in patients with some thrombocytopenic conditions

Abstract

Background: Thrombocytopenia is one of the most frequent causes for hematologic consultation in the practice of medicine and can result from a wide variety of conditions. Objective: The study was conducted on behave of platelets count in tie with platelet volume indices to measure their consistency. Methods: The study was “prospective cross-sectional hospital based design” and conducted at Khartoum hospitals (A.Gasim, Jafar I A, and R.ICK). Studied populations texture has stipulated concurred diagnosis of heart disorders (HD), lymphoid neoplasms (LN), hypoplastic bone marrow (HPB), renal transplantation (RT), patients under chemotherapy (CT), and fully checked healthy Sudanese population (HSP). Platelet (PLT) count and platelet volume index (PVI) were measured using automated method of Sysmex KX-21N and the data was analyzed using SPSS. Results: does established (24) mean and standard for the study population among which (HSP) was platelet distribution width (PDW) (11.4±1.5 fl), mean platelet volume (MPV) (9.3±0.8 fl), platelet large cell ratio (PLCR) (20.6±6.7%) and PLT count (245±45 X109/L), and established correlations between PLT count and PVI in thrombocytopenic conditions. Conclusion: we conclude that, PVI has the ability to change from normal to higher or lower than (HSP) in thrombocytopenic conditions and Sudanese has PVI mean lower than the mean of reference range, and there are inverse and reverse correlations between PLT count and PVI but not in (HSP) and reverse correlation in between PVI except between PDW and P-LCR in (HPB)